Do Smallpox Vaccines Protect Against Mpox (Monkeypox)?

of vaccinia vaccines against smallpox and mpox today are the ACAM2000 vaccine and the JYNNEOS vaccine.
ACAM2000 vaccine
The ACAM2000 vaccine requires only one shot. This is basically the vaccine that weve had for quite some time says Dr. Esper. Its injected into a persons shoulder and it causes an infection in that shoulder. Your immune system will then eliminate it and learn how to protect against smallpox and any other pox virus that comes around like monkeypox. 
But higher risks come with this vaccine because the virus can replicate and spread to other parts of your body. If you get the ACAM2000 vaccine youll need to take precautions when caring for the vaccine site and not have close skintoskin contact with others. And youre only considered fully protected 28 days after the inoculation. 
ACAM2000 isnt recommended for children under the age of 1 people who are pregnant or people who are living with
Heart disease Eye disease treated with topical steroids Immune deficiency disorders including HIV. Atopic dermatitis eczema or a history of acute or exfoliative skin conditions.
JYNNEOS vaccine
The newer vaccine JYNNEOS also known as Imvamune or Imvanex was licensed by the U S. Food and Drug Administration FDA in 2019 for the prevention of both smallpox and mpox in adults. Its considered a safer form of vaccine if youre immunocompromised or have any of the above conditions.
It basically just goes into the skin and doesnt replicate notes Dr. Esper. Then your immune system learns how to protect itself from that virus. Its similar to a flu shot.
This vaccine has a lower risk of side effects. It requires two shots spaced four weeks apart. Youre considered fully immune two weeks after your second dose. Theres currently a limited supply of JYNNEOS but more is expected in the next few months. The U S. Department of Health and Human Services plans to distribute a total of more than 4 million JYNNEOS doses in 2022 and 2023.
Is mpox monkeypox the same as smallpox?
Youre not seeing spots mpox and smallpox are in fact different. But theyre actually siblings of the same family called orthopoxvirus or poxvirus.
The big difference? Mpox is far less severe and is rarely ever fatal. 
Most people infected with monkeypox will have a mild disease Dr. Ross says. There is probably a large pool of people who are infected and dont realize it because they have minor symptoms and only one or